Chemistry: Graduate Lecture Series: (AO4) Advanced Heterocyclic Chemistry (5L)

ADVANCED ORGANIC CHEMISTRY (AO)

These lectures will build upon the classic methods of heterocyclic synthesis taught at the undergraduate level. Lecture 1 will begin with a more conceptual focus, discuss why new routes to heterocycles are required and the factors that often contribute to a 'good' synthesis such as modularity, versatility and functional group tolerance and whether to install substituents pre or post-formation of the heterocycle. Lecture 2 will focus on the synthesis of monocyclic systems and the application of some more modern reactions to make these systems, particularly reactions involving transition metal catalysis. Lecture 3 will focus on the synthesis of bicyclic systems with a similar emphasis on the use of more modern reactions to access these systems. Lecture 4 will investigate more saturated heterocyclic systems and the challenges and opportunities that these bring. Lecture 5 will look at some of the modern applications of heterocycles, particularly in terms of ligands for catalysis, supramolecular chemistry and chemical biology.

Postgraduates in the Department of Chemistry

Lecture

1 hour