Department of Chemistry course timetable
May 2017
| Wed 24 |
DD6 Toxicity and Drug Safety
Finished
Drug safety remains the primary cause of compound attrition when developing new medicines and consequently the ability to understand and predict toxicity is regarded as high priority within the pharmaceutical sector. This lecture will describe some common safety liabilities and ongoing work to build a greater understanding of the relationships between chemical structure and toxicity risk that are being harnessed to guide the design of safer compounds Dr R Ian Storer - AstraZeneca |
| Thu 25 |
AthenaSWAN Event
Finished
Following our recent straw poll on how members of the Department would like to meet up and discuss issues relating to gender equality in our Department, this mixed gender meeting invites you to come and contribute to a discussion session over lunch. The questions and issues to be discussed will be generated through people filling out this Anonymous Survey and all ideas/suggestions produced during the meeting will be taken to the AthenaSWAN Committee for discussion, potential approval and implementation. |
| Fri 26 |
DD7 Kinase Inhibitor Case Studies
Finished
Kinase drug discovery remains to be an area of significant and growing interest across academia and in the pharmaceutical industry - there are approximately 30 FDA approved small molecule inhibitors which target kinases, half of which were approved in the last 3 years. This lecture will give an insight into the medicinal chemistry story behind one clinical candidate and 2 marketed drugs. Crystal structures will be used to explain general principles behind designing for kinase inhibition, and some more advanced topics will be covered such as prodrugs, covalent inhibition and consideration of mutation status in drug discovery Dr F Goldberg - AstraZeneca |
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Are you a post-doc applying for grants? Do you need to write a Data Management Plan as part of your grant application but don't know how? Are you a post-doc who is just interested in learning about writing data management plans? If so, this session is for you. During this session you will learn everything you need to know about data management plans:
Refreshments will be provided (tea, coffee, and biscuits). |
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| Wed 31 |
DD8 Agrochemical Discovery
Finished
As the world population continues to grow, so does the need to increase global food production sustainably with limited resources. Agrochemicals, in the form of herbicides, fungicides and insecticides, provide an important tool for farmers to combat the weeds, fungi and insect pests that target their crops and help to ensure reliable yields and quality produce. Resistance, emerging pests, abiotic stress and regulatory pressure all drive an ongoing search for new and more innovative crop protection products. This lecture will outline the process used to discover new agrochemicals, from lead generation through to development. It will show the critical roles that chemistry, biology and human & environmental safety play, illustrated with a number of recent examples. Dr Steve Smith - Syngenta |
June 2017
| Fri 2 |
DD9 Process Chemistry
Finished
Two complementary lectures, between which tea, coffee and biscuits will be provided for all participants, industry experts on process chemistry from GSK and Syngenta will share their experiences and challenges gathered over many years of experience |
| Tue 6 |
FS21 Your Training Record
Finished
If you are not sure what the Training Record is for, why it is a good idea to use it (as well as filling it in because you need to submit it alongside your first year report) and why it is now an excel spreadsheet and not a paper log book with a blue cover (as all the previous years were issued with), please come to this session. Deborah will give a brief talk and background to these things and answer questions from attendees for the remainder of the time. |
| Wed 7 |
FS19 Writing Up Wednesdays
Finished
Three drop-in sessions will be held in the direct run up to first year report submission, in order primarily to provide students with the opportunity to come and ask questions about any aspect of the first year report submission process that is not clear to them. However, any student with any query is welcome to turn up and see a combination of at least two of those listed above: we will endeavor to help you with anything you ask us about. |
| Thu 8 |
Submission of the PhD thesis can seem to be a daunting experience, from constructing it to submitting and then being examined, with one of those examiners coming from an external institution. In this session, Marie Dixon (Degree Committee Office, School of Physical Sciences), Rachel MacDonald and Deborah Longbottom will talk through all aspects of procedure regarding thesis submission and answer any questions students wish to pose. Students who were recently examined, as well as members of academic staff who carry out PhD vivas will also be there to talk about the reality of the process from all perspectives |
| Tue 13 |
DD10 Process Chemistry Workshops
Finished
In these sessions, Dr. Mukund S. Chorghade will discuss the pivotal role played by Process Chemistry / Route Selection in the progress of a drug from conception to commercialization. The medicinal chemistry routes for synthesis are usually low yielding and are fraught with capricious reactions, cryogenic temperatures, tedious chromatography and problems in scale-up to multi-kilo and multi-ton levels. Considerable research efforts have to be expended in developing novel, cost efficacious and scalable processes and seamlessly transferring these technologies to manufacturing operations. These principles will be exemplified by process development case studies on a variety of pharmaceutical moieties such as anti-epileptic and an anti-asthma drugs |
| Wed 14 |
DD10 Process Chemistry Workshops
Finished
In these sessions, Dr. Mukund S. Chorghade will discuss the pivotal role played by Process Chemistry / Route Selection in the progress of a drug from conception to commercialization. The medicinal chemistry routes for synthesis are usually low yielding and are fraught with capricious reactions, cryogenic temperatures, tedious chromatography and problems in scale-up to multi-kilo and multi-ton levels. Considerable research efforts have to be expended in developing novel, cost efficacious and scalable processes and seamlessly transferring these technologies to manufacturing operations. These principles will be exemplified by process development case studies on a variety of pharmaceutical moieties such as anti-epileptic and an anti-asthma drugs |
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FS19 Writing Up Wednesdays
Finished
Three drop-in sessions will be held in the direct run up to first year report submission, in order primarily to provide students with the opportunity to come and ask questions about any aspect of the first year report submission process that is not clear to them. However, any student with any query is welcome to turn up and see a combination of at least two of those listed above: we will endeavor to help you with anything you ask us about. |
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| Fri 16 |
A one day course that explores the considerable research that has been done into leadership and the ways to develop individual leadership skills. The challenges of leadership will be discussed and participants will gain an appreciation of effective leadership behaviour, as well as being given the opportunity to discuss and develop their own approaches to being a leader. The Course Leader is Roger Sutherland, previously an HR Director for Mars Incorporated, and highly experienced in running courses for senior universities and companies |
| Wed 21 |
FS19 Writing Up Wednesdays
Finished
Three drop-in sessions will be held in the direct run up to first year report submission, in order primarily to provide students with the opportunity to come and ask questions about any aspect of the first year report submission process that is not clear to them. However, any student with any query is welcome to turn up and see a combination of at least two of those listed above: we will endeavor to help you with anything you ask us about. |
July 2017
| Tue 4 |
AO1 is a 3 part series, which runs over the course of three years in rotation and sees Molecular Orbitals in Organic Chemistry (the first part) being given this year. These lectures do not need to be taken in order. The series is as follows: AO1 Part 1. Molecular Orbitals in Organic Chemistry (4L, current) These lectures introduce molecular orbitals – the fundamental description of electron distribution that chemists use to explain chemical bonding and chemical reactivity. There is no mathematics, only the basic physics. Topics include s-bonding, p-conjugation using the Hückel picture, hard and soft acids and bases, and reactivity using, with some circumspection, frontier orbital theory and the Salem-Klopman equation. AO1 Part 2. Stereospecific Reactions in Organic Synthesis (4L, 2018) These lectures describe how the sense and degree of stereospecificity in several fundamental chemical reactions – substitution, elimination and addition – and the sense and degree of stereoselectivity in others – nucleophilic and electrophilic attack on double bonds with diastereotopic surfaces – can be explained by considering the molecular orbitals involved. AO1 Part 3. Pericyclic Reactions (4L, 2019) These lectures continue the subject of stereospecificity, which is seen in its most powerful form in pericyclic reactions. The four classes of pericyclic reaction are described, and their allowedness and stereochemistry explained. The Woodward-Hoffmann rule is illustrated with the most telling examples. |
| Thu 6 |
AO1 is a 3 part series, which runs over the course of three years in rotation and sees Molecular Orbitals in Organic Chemistry (the first part) being given this year. These lectures do not need to be taken in order. The series is as follows: AO1 Part 1. Molecular Orbitals in Organic Chemistry (4L, current) These lectures introduce molecular orbitals – the fundamental description of electron distribution that chemists use to explain chemical bonding and chemical reactivity. There is no mathematics, only the basic physics. Topics include s-bonding, p-conjugation using the Hückel picture, hard and soft acids and bases, and reactivity using, with some circumspection, frontier orbital theory and the Salem-Klopman equation. AO1 Part 2. Stereospecific Reactions in Organic Synthesis (4L, 2018) These lectures describe how the sense and degree of stereospecificity in several fundamental chemical reactions – substitution, elimination and addition – and the sense and degree of stereoselectivity in others – nucleophilic and electrophilic attack on double bonds with diastereotopic surfaces – can be explained by considering the molecular orbitals involved. AO1 Part 3. Pericyclic Reactions (4L, 2019) These lectures continue the subject of stereospecificity, which is seen in its most powerful form in pericyclic reactions. The four classes of pericyclic reaction are described, and their allowedness and stereochemistry explained. The Woodward-Hoffmann rule is illustrated with the most telling examples. |
| Tue 11 |
AO1 is a 3 part series, which runs over the course of three years in rotation and sees Molecular Orbitals in Organic Chemistry (the first part) being given this year. These lectures do not need to be taken in order. The series is as follows: AO1 Part 1. Molecular Orbitals in Organic Chemistry (4L, current) These lectures introduce molecular orbitals – the fundamental description of electron distribution that chemists use to explain chemical bonding and chemical reactivity. There is no mathematics, only the basic physics. Topics include s-bonding, p-conjugation using the Hückel picture, hard and soft acids and bases, and reactivity using, with some circumspection, frontier orbital theory and the Salem-Klopman equation. AO1 Part 2. Stereospecific Reactions in Organic Synthesis (4L, 2018) These lectures describe how the sense and degree of stereospecificity in several fundamental chemical reactions – substitution, elimination and addition – and the sense and degree of stereoselectivity in others – nucleophilic and electrophilic attack on double bonds with diastereotopic surfaces – can be explained by considering the molecular orbitals involved. AO1 Part 3. Pericyclic Reactions (4L, 2019) These lectures continue the subject of stereospecificity, which is seen in its most powerful form in pericyclic reactions. The four classes of pericyclic reaction are described, and their allowedness and stereochemistry explained. The Woodward-Hoffmann rule is illustrated with the most telling examples. |
| Thu 13 |
AO1 is a 3 part series, which runs over the course of three years in rotation and sees Molecular Orbitals in Organic Chemistry (the first part) being given this year. These lectures do not need to be taken in order. The series is as follows: AO1 Part 1. Molecular Orbitals in Organic Chemistry (4L, current) These lectures introduce molecular orbitals – the fundamental description of electron distribution that chemists use to explain chemical bonding and chemical reactivity. There is no mathematics, only the basic physics. Topics include s-bonding, p-conjugation using the Hückel picture, hard and soft acids and bases, and reactivity using, with some circumspection, frontier orbital theory and the Salem-Klopman equation. AO1 Part 2. Stereospecific Reactions in Organic Synthesis (4L, 2018) These lectures describe how the sense and degree of stereospecificity in several fundamental chemical reactions – substitution, elimination and addition – and the sense and degree of stereoselectivity in others – nucleophilic and electrophilic attack on double bonds with diastereotopic surfaces – can be explained by considering the molecular orbitals involved. AO1 Part 3. Pericyclic Reactions (4L, 2019) These lectures continue the subject of stereospecificity, which is seen in its most powerful form in pericyclic reactions. The four classes of pericyclic reaction are described, and their allowedness and stereochemistry explained. The Woodward-Hoffmann rule is illustrated with the most telling examples. |
October 2017
| Mon 2 |
SF1 Safety Induction
Finished
Part of Induction Week |
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SF1 Safety Induction
Finished
Part of Induction Week |
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| Tue 3 |
FS8 Supervising Undergraduates
Finished
In this short talk we will cover what supervisions are, the role they play in Cambridge teaching, and how supervisors are recruited. We will then go on to look at how you can prepare for supervising, how you can conduct a supervision, and how to deal with common pitfalls. |
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For new PhD students within the Chemistry Department |
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| Wed 4 |
For new PhD students within the Chemistry Department |
| Mon 9 |
This compulsory session introduces new graduate students to the Department of Chemistry Library and its place within the wider Cambridge University Library system. It provides general information on what is available, where it is, and how to get it. Print and online resources are included. |
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This session is compulsory for all experimentalists to attend and will provide useful information regarding analytical facilities at this Department including NMR, mass spectrometry and X-ray crystallography. Short descriptions will be given of all available instruments, together with a tour to show participants where these instruments are located, as well as explain the procedures for preparing/submitting samples for the analysis will also be discussed. |